Ovine footrot: A review of current knowledge
نویسندگان
چکیده
• Ovine footrot is a contagious disease with important economic and welfare impacts. Typical signs are lameness, interdigital inflammation underrunning of the horn. Transmission Dichelobacter nodosus favoured by warm, wet environments. aprV2/aprB2 genes targets for PCR diagnosis virulent vs. benign strains. Control measures culling, footbathing, vaccination antimicrobial treatment. Footrot foot mainly affecting sheep. It caused Gram-negative anaerobic bacterium nodosus. Warm, environmental conditions favour development footrot, under perfect conditions, it takes just 2–3 weeks from infection to manifestation clinical signs. Affected sheep show lameness various degrees often graze while resting on their carpi. Local vary in severity extent (benign footrot) complete horn shoe advanced stages footrot. Laboratory ideally involves collection four-foot swab samples followed competitive real time PCR, allowing detection presence D. differentiation between Laboratory-based diagnostics at flock level based risk-based sampling pooling recommended. The list treatment options individual includes careful removal loose undermined horn, local or systemic administration antimicrobials, non-steroidal anti-inflammatories (NSAIDs) disinfectant footbathing. Strategies control manifold depend procedures traditionally implemented respective country. Generally, consist treatment/culling infected sheep, prevention reinfection disease-free flocks. Gaining deeper insight into beneficial effects NSAIDs, screening eco-friendly footbath solutions, developing better vaccines, including robust, reproducible model elucidation protective immune responses, as well elaboration effective awareness training programs farmers, relevant research gaps.
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ژورنال
عنوان ژورنال: Veterinary Journal
سال: 2021
ISSN: ['1090-0233', '1532-2971']
DOI: https://doi.org/10.1016/j.tvjl.2021.105647